Fig 2: a) Four Balbiani granules are shown, one of which is labeled for KRIT1 at the periphery; terbium staining; scale bar: 50 nm. b) HeLa cell double labeled for m3Gcap (small grains) and KRIT1 (large grains); in some cases (arrow) we can observe a colocalization; EDTA staining; scale bar: 100 nm. c) Rat liver after EDTA staining; a nuclear domain is shown with a strong labeling for KRIT1; scale bar: 100 nm. d) A similar nuclear domain, terbium stained, is present in a HeLa cell; also in this case a heavy labeling for KRIT1 is present; scale bar: 100 nm. e) Labeling for KRIT1 in the nucleolus of a HeLa cells; the grains are present on the dense fibrillar component; scale bar: 200 nm. f) Part of a nucleolus of a Hela cell nucleus; KRIT1 is present in the dense fibrillar component surrounding the fibrillar center (Fc); terbium staining; scale bar: 50 nm.